Folic Acid Inhibitors
- 06-01-2016
- 02:08
- Antibiotics
Folic Acid Inhibitors
Dihydropteroate enzyme catalyze the synthesis of bacterial folic acid. Sulfonamide antibiotics inhibit dihydropteroate enzyme thus interfere with folic acid synthesis. Dihydrofolate reductase catalyze the conversion of tetrahydrofolic acid in human and ba