Proton Pump Inhibitors

  • 06-01-2016
  • 03:25
  • Miscellaneous

Proton Pump Inhibitors

Proton pumps (H/K ATPase) in the parietal is the main regulator of gastric acidity. It excrete hydrogen into parietal cells in exchange of K ions. Gastrin, acetycholine and histamine H2 enhance the activity whereas prostaglandins E2 diminish the activity

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