Proton Pump Inhibitors
- 06-01-2016
- 03:25
- Miscellaneous
Proton Pump Inhibitors
Proton pumps (H/K ATPase) in the parietal is the main regulator of gastric acidity. It excrete hydrogen into parietal cells in exchange of K ions. Gastrin, acetycholine and histamine H2 enhance the activity whereas prostaglandins E2 diminish the activity