General Immunosuppressant Agents

  • 06-01-2016
  • 03:16
  • Cancer and Immunity

General Immunosuppressant Agents

Binding of antigen presenting cells to t cells results in activation calcineurin enzyme which activate NAFTc. Active NFATc travel to nucleus and promote the release of IL-2 mRNA. The released IL-2 actiavte mTOR which enhance cellular proliferation. Cyclos

Tags: immunosuppressant , cyclosporine , sirolimus , calcineurin , nfatc , mtor ,

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