Find: fibrin


Binding of ATP to its receptors in the platelet surface activate cascade of reactions which end up by activation of the glycoprotein receptors on the platelet surface which mediate the aggregation of fibrin strands to platelet. Clopidogel inhibits the bin


Drug for hyperlipidemia. It decreases LDL synthesis, Increases fatty acid degradation. Decreases TAG formation. Additionally it enhance synthesis of apoproteins AI and AII which result in enhancement of HDL synthesis.

Fibrin Degradation

Fibrinogen is activated into fibrin strands which cluster together to form stable net. Prothrombin is activated into thrombin which the formation of fibrin net. Plasminogen is activated into plasminogen which degrade the fibrin net.

Gp IIb-IIIa Inhibitors

Fibrinogen binds to GP IIb-IIIa receptors on the platelets surface and play important role in platelet aggregation. GP IIb-IIIa inhibitors inhibit the binding of fibrinogen to platelets and thus interfere with platelet aggregation.